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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Binding coefficient ： ウィキペディア英語版 Binding coefficient In medicinal chemistry and pharmacology, a binding coefficient is a quantity representing the extent to which a chemical compound will bind to a macromolecule.〔Schurr JM, Rangel DP, Aragon SR. (2005) ("A Contribution to the Theory of Preferential Interaction Coefficients." ) ''Biophysical Journal.'' 89:2258-2276.〕〔Shulgin IL, Ruckenstein E (2006) ("A Protein Molecule in a Mixed Solvent: The Preferential Binding Parameter via the Kirkwood-Buff theory." ) ''Biophysical Journal.'' 90:704–707.〕 The preferential binding coefficient can be derived from the Kirkwood-Buff solution theory of solutions. Preferential binding is defined as a thermodynamic expression that describes the binding of the cosolvent over the solvent. This is in a system that is open to both the solvent and cosolvent. 〔 Pierce V, Kang M, Weerasinghe S, Smith PE. (2008) ("Recent Applications of Kirkwood-Buff Theory to Biological Systems." ) ''Cell Biochem Biophys.'' 50(1):1-22.〕 Consequently, preferential interaction coefficients are measures of interactions that involve “solutes that participate in a reaction in solution.” 〔Thomas Record Jr. M, Anderson CF. (1995) ("Interpretation of Preferential Interaction Coefficients of Nonelectrolytes and of Electrolyte Ions in Terms of a Two-Domain Model." ) ''Biophysical Journal.'' 68:786-794.〕 == See also == * Binding constant * Partition coefficient * Binding affinity 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Binding coefficient」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.